Beltrami Antonio Paolo
Personal information
First name(s) / Surname(s)
Antonio Paolo Beltrami
Address(es)
Via della Coda,16, 33100 Pagnacco (UD)
Telephone(s)
+390432559477
antonio.beltrami [at] uniud.it
Nationality
Italian
Place and date of birth
Bologna (Italy), January, 25th 1973
Gender
Male
Occupational field
Scientist (Assistant Professor; 2014: professional qualification to Associate Professor)
Work experience
Dates
2008-now
Occupation or position held
Assistant Professor
Main activities and responsibilities
Research and Teaching
Name and address of employer
Università degli Studi di Udine,
Since January 2010: Dipartimento di Scienze Mediche e Biologiche
2008-2010: Dipartimento Ricerche Mediche e Morfologiche
P.le Kolbe, 4 -33100 Udine
Type of business or sector
Public Research
Dates
2006-2008
Occupation or position held
Post-doctorate Fellow
Main activities and responsibilities
Research
Name and address of employer
Università degli Studi di Udine,
Dipartimento Ricerche Mediche e Morfologiche
P.le Kolbe, 4 -33100 Udine
Type of business or sector
Public Research
Education and training
Dates
2002-2006
Title of qualification awarded
Residency in Hematology; Final grade: 70/70 with honors
Principal subjects/occupational skills covered
Laboratory testing in hematology
Research
Name and type of organisation providing education and training
Università degli Studi di Udine,
Dipartimento Ricerche Mediche e Morfologiche
P.le Kolbe, 4 -33100 Udine
Dates
2000-2003
Title of qualification awarded
PhD Student in “Clinical Sciences and Technologies”
Principal subjects/occupational skills covered
Stem cell biology
Histology
Immunofluorescence
Confocal microscopy
Flow-cytometry
Cell Sorting
Cell Cloning
Retroviral based gene transfer
Cardiovascular physiology
Name and type of organisation providing education and training
Università degli Studi di Udine, Dipartimento di Patologia Medicina Sperimentale e Clinica, p.le S. Maria della Misericordia, 33100 Udine;
New York Medical College, Cardiovascular Research Insititute, Vosburgh Pavillion 302 A, Valhalla, NY 10595
Dates
1991-1999
Title of qualification awarded
Medical Doctor; Final grade: 110/110 with honors
Principal subjects/occupational skills covered
Human Biology, Anatomy, Physiology, Pathology, Medical Therapy, and Surgical Therapy.
Name and type of organisation providing education and training
Facoltà di Medicina e Chirurgia, Università degli Studi di Udine, Via Colugna, 50 - 33100 UDINE
Dates
1989-1991
Title of qualification awarded
Maturità Scientifica
Principal subjects/occupational skills covered
Italian grammar and literature, Latin grammar and literature, English grammar and literature, History, Mathematics, Chemistry, Biology, Art history.
Name and type of organisation providing education and training
Liceo Scientifico N. Copernico, viale Ungheria, 33100 Udine
Dates
1986-1989
Title of qualification awarded
Liceo Scientifico (moved to Udine and continued there)
Principal subjects/occupational skills covered
Italian grammar and literature, Latin grammar and literature, English grammar and literature, History, Mathematics, Chemistry, Biology, Art history.
Name and type of organisation providing education and training
Liceo Scientifico G. Galilei, viale Ungheria, 33100 Udine, Via Brecce Bianche, 72 - 60131 Ancona
Fellowships and awards
Date
2004
Award
National Innovation Prize received from a federation of Italian Universities as a co-founder of a Spin-off of the University of Udine named “Tissue and Organ Replacement”- T.O.R.
Date
2004
Award
StartCup Award received from the University of Udine and “Fondazione Cassa di Risparmio di Udine e Pordenone” (Italy) as a co-founder of a Spin-off of the University of Udine named “Tissue and Organ Replacement”- T.O.R.
Date
2000-2003
Award
Research Scholarship, Cardiovascular Research Institute, Department of Medicine, New York Medical College, Valhalla (NY), USA
Dates
2006-2008
Award
Post-doctoral fellowship, Interdepartmental Centre for Regenerative Medicine, University of Udine, Italy
Date
2014
Award
Professional qualification to Associate Professor in Pathology awarded by the Italian Ministry for University and Research (MIUR)
Date
2017
Award
Travel Grant from the Italian Society for Cardiovascular Research (SIRC).
Mother tongue(s)
Italian
English
• Reading skills
Excellent
• Writing skills
Excellent
• Verbal skills
Excellent
Spanish
• Reading skills
Good
• Writing skills
Basic
• Verbal skills
Good
Social skills
and competences
[ Describe these competences and indicate where they were acquired. ]
I developed the ability to interact with other people in a multicultural environment working for three years in a multicultural laboratory (Cardiovascular Research Institute at New York Medical College), performing research as a team.
Organisational skills
and competences
.
I participated in projecting, writing, and managing the following grants;
a. Italian Ministry of the University and Research Project: PRIN 2004 pr.2004061130 (P.I. Carlo Alberto Beltrami); 2004-2006. Title: “Study on the role played by cells and microenvironment in regenerative medicine and cell therapy”.
b. Italian Ministry of the Health: P.R.F. 10/04 (P.I. Carlo Alberto Beltrami); 2004-2006. Title: “Identification, characterization, in vitro growth and therapeutical utilization of human multipotent mesenchymal cells”
c. Italian Association for the Cancer Research (AIRC): Regional Grant 2005 pr.1023 (P.I. Antonio Amoroso); 2005-2007. Title: “New approaches for studying genetics, early molecular diagnosis and prognostic factors relevant for HCC”
d. Friuli Venezia Giulia Regional Grant: Art.11 L.R. 11/2003 (P.I. Carlo Alberto Beltrami); 2006-2008. Title: “Stem cell characterization and utilization, through tissue engineering technologies, in human therapy.”
e. Italian Ministry of the University and Research Project: PRIN 2006 pr. 2006060854 (P.I. Carlo Alberto Beltrami); 2006-2008. Title:“Cellule staminali mesenchimali (MSC) e cellule staminali mesenchimali pluripotenti dell'adulto (PMSC): biologia, immunomodulazione dei trapianti e ingegneria tissutale”.
f. Department of Health, Regione FVG: “Therapeutic use of Multipotent Adult Stem Cells” 2008-2009
g. Italian Ministry of the Health: “Giovani Ricercatori”. Impiego di cellule staminali multipotenti dell’adulto da tessuto adipose per la rigenerazione cardiovascolare. GR-2007-683407 (P.I. Daniela Cesselli). 2008-2011.
h. Collaborator of the ERC advanced grant “MOlecular NAnotechnology for LIfe Science Applications: QUantitative Interactomics for Diagnostics, PROteomics and QUantitative Oncology”. P.I. Prof. Scoles.
i. Project Partner of a project financed by the Italian Ministry of the University and Research: FIRB accordi di programma 2011 pr. RBAP11ETKA_007 “Nanotechnological approaches for tumor theragnostic”. Coordinator: Maurizio Prato.
j. Project Partner of a cross-border cooperation program Italy-Slovenia 2007-2013 funded by the European Regional Development fund and national funds. Project title: “The cross-border proteins centre for cancer, diagnostic and research”. Acronym: PROTEO.
k. Project Partner of a cross-border cooperation program Italy-Slovenia 2007-2013 funded by the European Regional Development fund and national funds. Project title: “Identificazione di nuovi marcatori di cellule staminali tumorali a scopo diagnostico e terapeutico”. Acronym: GLIOMA.
l. Project Partner of a cross-border cooperation program Italy-Austria 2014-2020 funded by the European Regional Development fund and national funds. Project acronym: “EXOTHERA”.
m. Coordinator of a Research Unit of a project financed by CARIPLO foundation. Project title “BPIFB4 isoforms: possible genetic risk factor and therapeutic tool for human frailty”.
n. Project Partner of a cross-border cooperation program Italy-Slovenia 2014-2020 funded by the European Regional Development fund and national funds. Project acronym: “TRANSGLIOMA”.
Technical skills and competences
Cardiac histology, histochemistry, and morphometry.
Immunofluorescence and confocal microscopy.
Isolation of cardiomyocytes from rat, dog, and from human hearts.
Isolation and growth of cardiac stem cells from mouse, rat, dog, and human hearts.
Flow cytometry and flow sorting (FACS).
Cell based assays (e.g. migration, invasion, differentiation, proliferation, viability).
Retroviral-based gene transfer.
Molecular biology analytical techniques for nucleic acids and proteins.
Statistical analysis.
Computer skills and competences
Good abilty both in Windows based and MacOS based environments. Good knowledge of:
· Office and iWorks software,
· flow cytometry software (i.e. Summit and FlowJo),
· statistical software (Prism, JMP, SPSS),
· image analysis software (ImageJ),
· image editing (Photoshop)
Driving licence
Italian type “B” driving licence (for cars and vehicles whose total weight is less than 3.5 tons).
Teaching activities
Supervision of undergraduate students and post-doctoral fellows
2004 – 2014 9 Postdocs (Natascha Bergamin, Federica D’Aurizio, Patrizia Marcon, Silvia Rigo, Angela Caragnano, Barbara Toffoletto, Ivana Manini, Emmanouil Athanasakis, and Claudia Veneziano) and 8 PhD students (Silvia Rigo, Giuseppe Gianfranceschi, Elisa Avolio, Elisa Mazzega, Angela Caragnano, Alessandra Poz, Andrea Zanello, and Celeste Cervellin), Department of Medical and Morphological Sciences (until 2009), Department of Medical and Biological Sciences (2009-2016), Department of Medicine (2017-now), University of Udine, Italy.
Master degree courses
2009/2010; 2018 MSc in Stem cells and Regeneration programme of the University of Bristol, UK; taught module “Stem Cells in Cardiac and Skeletal Systems”.
2012; 2014-2017 Hematopoietic stem cells and regenerative medicine, University of Parma, Italy.
2017 Stem cells and regenerative medicine, University of Krems, Austria.
Lecturer
2009 – 2011 1) Pathology, 2) Stem cell culture, and 3) Regenerative medicine courses, I and II level Biotechnology degree, University of Udine, Italy; Surgical Pathology, Laboratory technician degree, University of Udine, Italy.
2011 – 2013 Surgical Pathology, Laboratory technician degree, University of Udine, Italy
2011/2012 Stem cells, Excellence School “Scuola Superiore” of the University of Udine.
2012 – 2014 1) Stem cells and regenerative medicine and 2) Molecular Diagnosis modules, I and II level Biotechnology degree, University of Udine, Italy.
2015-2016 1) Stem cells and regenerative medicine and 2) Molecular Diagnosis modules, I and II level Biotechnology degree, University of Udine, Italy. Surgical Pathology, Faculty of Medicine.
2017 1) Disease models, 2) Stem cells and regenerative medicine and 3) Molecular Diagnosis modules, I and II level Biotechnology degrees, University of Udine, Italy. Surgical Pathology, Faculty of Medicine.
2018 1) Disease models, 2) Molecular Diagnosis courses, I and II level Biotechnology modules, University of Udine, Italy. Surgical Pathology, Faculty of Medicine.
Institutional responsibilities
Dates
2008-2016
Faculty member, Department of Medical and Biological Sciences, University of Udine, Italy.
Member of the committee for the didactics of the II degree level of Biotechnology.
Dates
2017-now
Faculty member, PhD School in “Food and human health”, University of Udine, Italy.
Dates
2017-now
Faculty member, Department of Medicine, University of Udine, Italy.
Editor and Reviewer activities
Academic Editor for Frontiers in Cardiovascular Medicine
Academic Editor for PlosONE
Peer-Reviewer of Scientific Reports, Elsevier, PlosONE, and International Journal of Nanomedicine.
Ad hoc reviewer for the following journals: Nature Clinical Practice Cardiovascular Medicine, Circulation, Pharmacology & Therapeutics, Differentiation, Journal of Cellular and Molecular Medicine, Cell Biology International, American Journal of Hypertension, Expert Opinion in Biological Therapy, Journal of Nephrology, Journal of Cardiovascular Translational Research, Acta Pharmacologica Sinica, and Tissue and Cell.
Reviewer for grant applications for: Diabetes UK; The Netherlands Organisation for Health Research and Development; New Zealand Heart Foundation; Agence National de la Recherche (ANR), France; Italian Ministry of University and Research (MIUR); and University of Padua, Italy.
Member of the evaluation committee for the Unit INSERM UMR 1087 l’institut du thorax on behalf of the Haute conseil de l’évaluation de la recherche et de l’enseignement supérieur (HCERES)
Active collaborations
1. Paolo Madeddu, cardiac cell therapy, stem cell biology of the heart, Chair Experimental Cardiovascular Medicine, Head of Regenerative Medicine Section, Bristol Heart Institute, School of Clinical Sciences, University of Bristol
2. Annibale Puca, role of BPIFB4 in cardiac stem cell biology and heart failure, Dipartimento di Medicina, Chirurgia e Odontoiatria "Scuola Medica Salernitana". Università degli Studi di Salerno e I.R.C.C.S. Multimedica, Milano.
3. Nicola Elvassore, mechanotransduction properties of human cardiac stem cells, Department of Industrial Engineering, University of Padua, Italy
5. Michele Morgante, next generation sequencing of human stem cells and exosomes, Insitute of Applied Genomics (IGA), University of Udine, Italy
6. Stefano Gustincich, role played by mobile elements and non-coding RNAs in stem cell differentiation, Area of Neurobiology, International School for Advanced Studies (SISSA), Trieste, Italy
7. Gianfranco Sinagra, pathophysiology of idiopathic dilated cardiomyopathies, Chair Cardiology, University of Trieste, Italy
8. Marco Lazzarino, biophysical characterization of stem cells isolated from gliomas, TASC/CNR, Trieste, Italy
9. Loredana Casalis, characterization of exosmes, and development of nanosensors for the detection of proteins and miRNA in biologic samples, Nanoinnovation Lab, Elettra/Sincrotrone, Trieste
10. Maurizio Pesce, effects of mechanotransduction on cardiac stem cell biology, Tissue engineering unit, Centro Cardiologico Monzino (CCM), Milan, Italy
11. Silvano Piazza and Yari Ciani, bioinformatics analysis of gene expression, Laboratorio Nazionale Consorzio Interateneo Biotecnologie (LNCIB), Trieste, Italy
12. Marco Meloni, use of Nerve Growth Factor for stem cell mobilization, Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK
13. Enrico Ferrari, Atomic force microscopy-based characterization of cells and exosomes, University of Lincoln, UK
14. Ario De Marco, Application of lama nanobodies in stem cell and cancer research, Centre for biomedical sciences and engineering, University of Nova Gorica, Slovenia
15. Tamara Lah, Use of stem cell technologies for the improvement of diagnosis and therapy of glioma, Director of the National Institute of Biology, Lubiana, Slovenia.
Additional information
Participation to Spin-off
2004: Co-founder of “Tissue and Organ Replacement” -T.O.R.-
Organization of Scientific Meetings
2006: Faculty member of the Summer School “Advanced topics in molecular medicine”. Organized with: Consortium for Biomolecular Medicine (CBM) and AREA Science Park (Trieste, Italy) together with Central European Initiative / 20 International Students / Italy
2003-14: Organizer of Biotechnology Seminars, Academic Hospital of Udine and University of Udine, Italy
Invited speaker
2018: Cardiocentro Lugano
2017: Italian Society for Cardiovascular Research (SIRC) XXI meeting, Imola, Italy.
2017: European Society of Cardiology annual meeting, Barcelona, Spain.
2016: Lugano Stem Cell Meeting, Switzerland.
2016: The Company of Biologists workshop on “Transdifferentiation and Tissue Plasticity in Cardiovascular Rejuvenation”, Whiston House, Steining, West Sussex, UK.
2015: National Congress of the Italian Society of Pharmacology, Naples
2015: Smart meeting anesthesia resuscitation intensive care, Milan, Italy
2013: German-Italian Centre for European Excellence; “Molecular and cellular regulators of cardiovascular homeostasis”, Villa Vigoni, Menaggio, Italy.
2013: National Cardiology Congress ANMCO, Firenze
2013: National Congress Italian Society of Pharmacology, Turin
2013: National Congress Italian Society of Cardiology, Rome
2012: Third Annual Robert and Arlene Kogod Center on Aging Conference: Senescence and Healthspan. Mayo Clinic, Rochester, MN, USA.
2012: “Tissue Remodeling in Ageing and Disease - Emerging Insights into a Complex Pathology” Meeting organized by the partners of the EU funded RESOLVE project.
2011: European Society of Cardiology workshop 'Cardiac Regeneration in Search of Cardiac Progenitors. Challenges of cell-based therapy for heart failure'.
2011: Kickoff meeting of the “QUIDPROQUO” ERC Advanced Grant.
2011: Adriatic Society of Pathology, Trieste.
2010: Lugano Stem Cell Meeting, Switzerland
2010: NATIONAL CONGRESS SIAPEC - IAP / Bologna
2009: 22nd EUROPEAN CONGRESS OF PATHOLOGY and NATIONAL CONGRESS SIAPEC - IAP / Florence
2009: Cellule staminali e medicina rigenerativa, Collegio Ghislieri, Pavia
2008: National Cardiology Congress ANMCO, Firenze
2008: Italian Society of Physiology National Congress, Cagliari
2007: Società Italiana Trapianti d’Organo, Modena
2007: Adriatic Society of Pathology, Ascoli Piceno
2005: NATIONAL CONGRESS SIAPEC - IAP / Chieti